Nathan Fillion - Capt. Malcolm "Mal" Reynolds
Gina Torres - Zoë Warren
Alan Tudyk - Hoban 'Wash' Washburne
Morena Baccarin - Inara Serra
Adam Baldwin - Jayne Cobb
Jewel Staite - Kaylee Frye
Sean Maher - Dr. Simon Tam
Summer Glau - River Tam
Ron Glass - Shepherd Book
Roma Chugani - Receiving Doctor
Dennis Cockrum - Blue Glove #2
Cate Cohen - Crash-Team Nurse
Alex Connie - Patient
Michael Nagy - Particularly Dressed Man
Jeff Ricketts - Blue Glove #1
Blake Robbins - Agent McGinnis
Ira Steck - Young Intern
Tom Virtue - Pompous Doctor