Nathan Fillion - Capt. Malcolm "Mal" Reynolds
Gina Torres - Zoë Warren
Alan Tudyk - Hoban 'Wash' Washburne
Morena Baccarin - Inara Serra
Adam Baldwin - Jayne Cobb
Jewel Staite - Kaylee Frye
Sean Maher - Dr. Simon Tam
Summer Glau - River Tam
Ron Glass - Shepherd Book
Andrew Bryniarski - Crow
Jeff Chase - Thug Contact (uncredited)
Dennis Cockrum - Blue Glove #2
Michael Fairman - Adelei Niska
Michelle Ferrara - Immigrant Woman #2
Drew Goddard - Guy on Planet (uncredited)
Tawny Rene Hamilton - Immigrant Woman #1
Gregg Henry - Sheriff Bourne
Eric Lange - Fed
Lina Patel - Ensign
Valerie Red-Horse - Deputy
David Reynolds - Henchman
Jeff Ricketts - Blue Glove #1
Stephen H. Silberkraus - Mud Farmer
Tom Towles - Lund
Kevin Will - Officer