Nathan Fillion - Capt. Malcolm "Mal" Reynolds
Gina Torres - Zoë Warren
Alan Tudyk - Hoban 'Wash' Washburne
Morena Baccarin - Inara Serra
Adam Baldwin - Jayne Cobb
Jewel Staite - Kaylee Frye
Sean Maher - Dr. Simon Tam
Summer Glau - River Tam
Ron Glass - Shepherd Book
John F. Kearney - Old Man
Kyle Kulish - Bookkeeper
Colin Patrick Lynch - Radio Operator
Jamie McShane - Man
Stephen O'Mahoney - Ensign #1
Greg Wendell Reid - Crying Soldier (uncredited)
Mark Sheppard - Badger (as Mark A. Sheppard)
Andy Umberger - Dortmunder Captain
Domingo Vara - Ensign #2
Gabrielle Wagner - Slave #1
Bonnie Bartlett - Patience
Carlos Jacott - Lawrence Dobson